The Burden of Non-Protocolized Patient Transport Outside of Response Area on a Rural Emergency Medical Services System

Objectives Prehospital transport decisions depend on a combination of protocols, judgment, and patient acuity/preference. Non-protocolized out-of-area transport may result in unnecessary delays and resource strain. Methods We retrospectively reviewed one year of scene transports by a rural, hospital-based EMS system, analyzing transport rationale and comparing hospital admission and specialist consultation as surrogates for decision appropriateness. …

GJA1-20K Reduces Levels of Interleukin-6 in Pigs with REBOA-Induced Ischemia-Reperfusion Injury

Introduction Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a resuscitation tool for noncompressible hemorrhage, preserving perfusion to the heart and brain while interrupting life-threatening blood losses. However, patients often suffer ischemia-reperfusion injury after balloon deflation. We previously demonstrated that the protein GJA1-20k protects the mitochondria and reduces serum interleukin-6 (IL-6), an inflammatory marker …